I have both a PayPal account and a 2Checkout account. I find that its much easier to access my funds when I use PayPal (with 2Checkout I have to wait on the cheque to be mailed each time). If it weren't for the fact that most of my customers prefer paying by credit card directly than going through PayPal I'd do away with the 2checkout account.

(By the way guys, I wouldnt advise you to keep too much money in your PayPal account at any one time, Ive heard too many stories of persons having their PayPal accounts 'frozen' without any clear reason as to why it was done.)