Hey there,

I think the header needs work, the light orange and the blue/white gradient don't really flow well together and it just looks messy. The rollover on the navigation is pretty pointless as it's hardly noticeable. Your logo looks like it's been stuck onto the header, gives a weird feeling. The header banner doesn't really have it's own position, it's just stuck there.

The side navigation is better but the white text for "Home" doesn't make much sense considering it's on a very light background. I prefer the blue scheme you're using for the newsletter part, that looks clean and would probably suit this site allover! The green colour used for the advertisement throws the rest of the colour scheme off.

The footer looks very templateish, not sure why the search is positioned right at the bottom of the page? Generally it should be full view the second the site loads.

The advertisements are very overwealming (not sure if this is intended or not)
and tend to grab my attention as opposed to reading the content.